19th ANNUAL EARLY HEARING DETECTION & INTERVENTION MEETING
March 8-10, 2020 • Kansas City, MO
Evaluation of Risk Factors Associated with Permanent Hearing Loss in Childhood: A Lesson from Louisiana Early Hearing Detection and Intervention Surveillance
The study aimed to evaluate risk factors associated with permanent congenital or delayed-onset hearing loss in childhood as indicated in ‘Year 2007 Position Statement: Principles and Guidelines for Early Hearing Detection and Intervention Programs - Joint Committee on Infant Hearing’. The 2017-2018 Louisiana Early Hearing Detection and Intervention data were used for analysis. Ten risk factors were evaluated including (1) family history of permanent childhood hearing loss, (2) neonatal intensive care (NICU) stay of more than 5 days, (3) extracorporeal membrane oxygenation, (4) assisted ventilation, (5) exposure to ototoxic medications, (6) hyperbilirubinemia that requires exchange transfusion, (7) congenital infections, (8) craniofacial anomalies, (9) physical findings /syndromes associated with hearing loss, and (10) culture-positive postnatal infections. Survival data analysis applying Cox proportional hazards regression model was used to evaluate statistical significance of risk factors. There were 117,592 children born between 2017 and 2018 included in the study. Of those, 193 (0.16%) children were diagnosed with permanent hearing loss (PHL). Prevalence of PHL varied among study risk factors. It was highest in children with physical findings/syndromes associated with hearing loss (9.76%), followed by craniofacial anomalies (6.36%), and assisted ventilation (2.30%). In the adjusted Cox regression model, five risk factors were statistically significant with PHL: family history of permanent childhood hearing loss (hazard ratio [HR]: 7.16; 95% confidence interval [CI]: 4.67-10.98), NICU stay of more than 5 days (HR: 3.61; CI: 2.49-5.24), craniofacial anomalies (HR: 11.18; CI: 6.12-20.44), physical findings/syndromes associated with hearing loss (HR: 7.34; CI: 3.58-15.05), and assisted ventilation (HR: 2.64; CI: 1.42-4.93). The analysis did not show statistical significance for other study risk factors of PHL. Rarity or underreporting of risk factors may explain the lack of associations in this study.
- Learn about risk factors of permanent congenital or delayed-onset hearing loss in childhood
- Understand how to collect these factors from EHDI surveillance
- Evaluate data collection of these fatcors
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Presenter: Tri Tran
Tri Tran, MD, MPH Senior Epidemiologist
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Qiaochu Xue, MPH Practicum student/Research Assistant
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Susannah Boudreaux, Program Manager BS
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Terri Ibieta, M.Ed. LA EHDI Program Coordinator
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Dawne McCabe, BS Data Coordinator
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Danielle Mercer, AuD System Development Coordinator
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