2022 Early Hearing Detection & Intervention Virtual Conference
March 13 - 15, 2022
8/23/2022 | 10:45 AM - 11:10 AM | National Congenital CMV (cCMV) Disease Registry - Texas Cases - Maternal Age is a Significant Risk F | Confederation II/III
National Congenital CMV (cCMV) Disease Registry - Texas Cases - Maternal Age is a Significant Risk F
Of 449 cCMV births in the state of Texas from 1982-2022 from the National Congenital CMV Disease Registry, 219 (49%) mothers were under age 25. Maternal age < 25 was a risk factor for prematurity (OR = 1.57, 95% CI = 1.04 to 2.37, p = .033) and low birthweight (LBW)(< 2500g) (OR = 2.40, 95% CI = 1.61 to 3.58, p < .001). Infants of younger non-Hispanic Black and White mothers, but not Hispanic mothers, had higher rates of prematurity, LBW and small-for-gestational-age (SGA) compared to mothers ? 25. Infants with LBW had significantly more cCMV symptoms than normal-weight infants: (mean (SD) symptoms = 5.0 (3.5) vs. 2.7 (2.7), p < .001); were more likely to have nervous system-related symptoms (62% vs 40%, p < .001) and liver-related symptoms (46.7% vs. 24.5%, p < .001) compared to normal-weight infants. Preterm infants (<37 weeks) also had more cCMV symptoms (mean (SD) = 4.6 (3.6) vs. 3.1 (3.1), p < .001), were more likely to have nervous system-related symptoms (60% vs 46%, p = .005) and liver-related symptoms (74% vs. 53%, p = .001) than term infants. Results indicate more severe cCMV disease in births to younger mothers, and suggest targets for prevention of cCMV and its adverse birth outcomes.
- Understand younger maternal age as a risk factor for more severe cCMV disease and adverse birth outcomes
- Low birthweight and premature birth increase risk of more cCMV symptoms at birth
- Identify targets for prevention of cCMV and its adverse birth outcomes
Presentation:
This presentation has not yet been uploaded.
Handouts:
Handout is not Available
Transcripts:
CART transcripts are NOT YET available, but will be posted shortly after the conference
Presenters/Authors
Gail Demmler-Harrison
(), gdemmler@bcm.edu;
Professor of Pediatrics at Baylor College of Medicine with over 30 years experience in the research and clinical management of infants with congenital CMV infection; PI of the HOuston Longitudinal Congenital CMV Followup Study; co author or author of numerous publicaitons, chapters and presenter at national and international meetings
ASHA DISCLOSURE:
Financial -
Nonfinancial -