2023 Early Hearing Detection & Intervention Conference
March 5-7, 2023 • Cincinnati, OH
5/21/2019 | 10:00 AM - 10:15 AM | FRESHWATER ENVIRONMENTS AS RESERVOIRS FOR ANTIBIOTIC RESISTANT BACTERIA AND GENES DISSEMINATION TO HUMAN PATHOGENS | 151 DEF
FRESHWATER ENVIRONMENTS AS RESERVOIRS FOR ANTIBIOTIC RESISTANT BACTERIA AND GENES DISSEMINATION TO HUMAN PATHOGENS
Freshwater environments are susceptible to possible contamination with residual antibiotics that are released through different sources, such as agricultural run-offs, sewage discharge and leaching from nearby farms. Unavoidably, they become reservoirs where antibiotics impact microorganisms that are indigenous to the environment. This has an important public health implication. This study evaluates the fate and persistence of antibiotic resistance bacteria and their resistance genes in freshwater environments. Factors that influence the antibiotic resistant bacteria (ARB) and antibiotic resistant genes (ARG) selection, development and persistence of ARBs and ARGs are poorly understood. Despite dilution and natural degradation process generally expected to reduce the level of ARGs in freshwater environment, yet there are important knowledge gaps to be filled. In order to improve risk assessment studies, the abundance and diversity of resistance genes is fundamental in order to estimate the actual risk of their dissemination from freshwater reservoirs to human pathogens (ii) Comprehend the causes and mechanisms driving the preservation and selection of antibiotics in freshwater habitats. Lastly, in this work suitable mitigation strategies are identified for freshwater environment antibiotic resistance development.
- Waterborne Pathogens
- Pollution
- Metagenomics
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Presenters/Authors
Chika Nnadozie
(), Institute for Water Reaseach, Rhodes University, Grahamstown, Eastern Cape, South Africa , c_nwaneri@yahoo.com;
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Nelson Odume
(), Institute for Water Research, Rhodes University, Grahamstown, South Africa, nelskaro@yahoo.com;
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