2023 Early Hearing Detection & Intervention Conference
March 5-7, 2023 • Cincinnati, OH
3/15/2022 | 2:30 PM - 3:00 PM | Clinical impact of genetics in sensorineural hearing loss | Room 1
Clinical impact of genetics in sensorineural hearing loss
Approximately 50% of all childhood sensorineural hearing loss (SNHL) is thought to be related to genetic differences. Both syndromic and non-syndromic SNHL can be caused by genetic variants, which are often detected by hearing-loss gene-panel testing (HL-CGT). Genetic diagnosis for hearing loss can inform prognosis, provide early identification of syndromic associations in apparently non-syndomic cases, enable family counseling, and allow for the recognition of health conditions that may warrant monitoring or care. Genetic diagnosis can help families understand their child’s hearing-loss, contributing to improved utilization of interventions for their child’s needs. Recent expansion of availability of HL-CGT has enabled new understanding of how genetic testing impacts the management of SNHL.
In this session, a pediatric otolaryngologist and developmental pediatrician will provide an overview of how genetics impacts management of non-syndromic and syndromic SNHL. This will include discussion of 1) how genetic testing impacts clinical decision-making for children with SNHL; 2) the relationship between genetic testing and syndromic forms of SNHL; and 3) the role of genetics in the context of children who are deaf with additional developmental delays. Participants will gain an understanding of the overall utility, role, and limitations of genetic testing in the care for children with SNHL.
- Understand how genetic testing impacts clinical decision-making for children with SNHL
- Learn the relationship between genetic testing and syndromic forms of SNHL
- Understand the role of genetics in the context of children who are deaf with additional developmental delays
Presentation:
3353554_15054DylanChan.pdf
Handouts:
Handout is not Available
Transcripts:
CART transcripts are NOT YET available, but will be posted shortly after the conference
Presenters/Authors
Dylan Chan
(InPerson), University of California, San Francisco, Department of Otolaryngology-Head and Neck Surgery, dylan.chan@ucsf.edu;
Dylan Chan, MD, PhD, FAAP, is Associate Professor and Director of the Children’s Communication Center (CCC) in the Department of Otolaryngology – Head and Neck Surgery at the University of California, San Francisco. He received his PhD in Auditory Neuroscience from the Rockefeller University and MD from Weill Medical College of Cornell University. Dr. Chan completed his ONHS residency from Stanford University, followed by a Pediatric Otolaryngology fellowship at Seattle Children’s Hospital. He is the AAP EHDI California Chapter 1 Champion and Regional Network Liaison for the AAP EHDI program in California.
In 2014, Dr. Chan established the UCSF Children’s Communication Center, which is devoted to delivering multidisciplinary care for families of deaf and hard of hearing children, performing community outreach and education, and conducting clinical and translational research projects. By addressing existing shortfalls in care delivery and developing novel interventions, he hopes to significantly impact hearing health in children.
ASHA DISCLOSURE:
Financial -
No relevant financial relationship exist.
Nonfinancial -
No relevant nonfinancial relationship exist.
Susan Wiley
(), Cincinnati Children's Hospital Medical Center, susan.wiley@cchmc.org;
Dr. Susan Wiley is a developmental pediatrician with extensive expertise in children who are deaf/hard of hearing. She has many years of experience serving children with multiple disabilities. Dr Wiley provides leadership and guidance to the National American Academy of Pediatrics, the Ohio Department of Health Early Hearing Detection and Intervention Program, the Ohio Center for Deaf-Blind Education, and the Outreach Center for Deafness and Blindness in the Ohio Center for Low Incidence.
ASHA DISCLOSURE:
Financial -
No relevant financial relationship exist.
Nonfinancial -
No relevant nonfinancial relationship exist.